Publications

PRECISION CHEMISTRY AND ACTIVITY-BASED PROTEOMICS FOR POSTTRANSLATIONAL CONTROL OF PROTEIN FUNCTION

Elizabeth M. Ryan, Michael A. Norinskiy, Amy K. Bracken, Emma E. Lueders, Xueer E. Chen, Qin Fu, Elizabeth T. Anderson, Sheng Zhang, Mikail E. Abbasov* Manuscript under review, 2024

INTEGRATED PHENOTYPIC AND ACTIVITY-BASED PROFILING OF ELECTROPHILIC FRAGMENTS REVEALS NEW TARGETS FOR ANTIBIOTICS DEVELOPMENT

Jin, Y., Jana, S., Abbasov, M. E.,* Lin, H.* Manuscript under review, 2024

Biomimetic synthesis and chemical proteomics reveal the mechanism of action and functional targets of phloroglucinol meroterpenoids

Bracken, A. K., Gekko, C. E., Suss, N. O., Lueders, E. E., Cui, Q., Fu, Q., Anderson, E. T., Zhang, S., Abbasov, M. E.*
J. Am. Chem. Soc. 2024 ,146, 4, 2524–2548.

A proteome-wide atlas of lysine-reactive chemistry

Abbasov, M. E., Kavanagh, M., Ichu, T.-A., Lazear, M. R., Tao, Y., Crowley, V. M., am Ende, C. W., Hacker, S. M., Ho, J., Dix, M. M., Suciu, R., Hayward, M. M., Kiessling, L. L., Cravatt, B. F.
Nat. Chem. 2021, 13, 1081–1092.

ENANTIOSELECTIVE, ORGANOCATALYTIC STRATEGY FOR THE OXAZOLOMYCIN CORE: FORMAL SYNTHESIS OF (+)- NEOOXAZOLOMYCIN

Chaheine, C. M., Gladen, P. T., Abbasov, M. E., Romo, D.
Org. Lett. 2020, 22, 9282–9286.

Simplified immunosuppressive and neuroprotective agents based on gracilin A

Abbasov, M. E., Alvariño, R.; Chaheine, C. M.; Alonso, E.; Sánchez, J. A.; Conner, M. L.; Alfonso, A.; Jaspars, M.; Botana, L. M.; Romo, D.
Nat. Chem. 2019, 11, 342–350.

Gracilin A derivatives target early events in Alzheimer’s disease: effects on neuroinflammation and oxidative stress

Alvariño, R., Alonso, E., Abbasov, M. E., Chaheine, C. M., Conner, M. L., Romo, D., Alfonso, A., Botana, L. M.
ACS Chem. Neurosci. 2019, 10, 4102–4111.

Enantioselective Diels-Alder-lactamization organocascades employing a furan-based diene

Abbasov, M. E., Hudson, B. M., Tantillo, D. J., Romo, D.
Org. Biomol. Chem. 2017, 15, 3179–3183.

Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application

Abbasov, M. E., Hudson, B. M., Tantillo, D. J., Romo, D.
Chem. Sci. 2017, 8, 1511–1524.

Acylammonium salts as dienophiles in Diels-Alder/lactonization organocascades

Abbasov, M. E., Hudson, B. M., Tantillo, D. J., Romo, D.
J. Am. Chem. Soc. 2014, 136, 4492–4495.

The ever-expanding role of asymmetric covalent organocatalysis in scalable, natural product synthesis

Abbasov, M. E., Romo, D.
Nat. Prod. Rep. 2014, 31, 1318–1327.

Effects of carbon nanotubes on electro-optical properties of dye-doped nematic liquid crystal

Abbasov, M. E., Carlisle, G. O.
J. Mater. Sci.: Mater. Electron. 2012, 23, 712–717.

Hybrid carbon nanotube and dye-doped liquid crystal material for holographic imaging

Abbasov, M. E., Ghosh, S., Quach, A., Carlisle, G. O.
J. Mater. Sci.: Mater. Electron. 2010, 21, 854–859.

Electric-field enhancement and modulation of permanent grating diffraction in dye and carbon nanotube-doped liquid crystal

Abbasov, M. E., Carlisle, G. O.
J. Nanophoton. 2008, 2, 023510.

Optical properties of permanent gratings in liquid crystal doped with dye and carbon nanotube

Suleiman, Y. S., Ghosh, S., Abbasov, M. E., Carlisle, G. O.
J. Mater. Sci.: Mater. Electron. 2008, 19, 662–668.

CHEMICAL ACYLATING AGENTS AND CHEMOPROTEOMIC METHODS FOR POSTTRANSLATIONAL MODULATION OF PROTEIN FUNCTION IN LIVE CELLS

Ryan, E. M., Norinskiy, M. A., Abbasov, M. E.
Provisional patent application filed on May 3, 2024. Docket No. 11135-01-US.

PHLOROGLUCINOL MEROTERPENOIDS AS LYSINE-TARGETING CHEMICAL PROBES FOR MODULATING MITOPHAGY AND DEGRADING BRCA1-MUTANT ONCOPROTEIN

Bracken, A. K., Gekko, C. E., Abbasov, M. E.
Provisional patent application filed on September 27, 2023. Docket No. 10898-01-US. App. No. 63/540, 783.

Gracilin A and congeners as immunosuppressive and neuroprotective agents

Abbasov, M. E., Alvariño, R., Alonso, E., Sánchez, J. A., Alfonso, A., Botana, L. M., Romo, D.
U.S. Application No. 62/638,856 (WO/2019/173382). March 5, 2018.