public

2024

Phenotypic screening of covalent compound libraries identifies chloromethyl ketone antibiotics and MiaA as a new target




Jin, Y., Jana, S., Abbasov, M. E.,* Lin, H.*
BioRvix 2024 DOI: 10.1101/2024.01.22.576576




Biomimetic synthesis and chemical proteomics reveal the mechanism of action and functional targets of phloroglucinol meroterpenoids




Bracken, A. K., Gekko, C. E., Suss, N. O., Lueders, E. E., Cui, Q., Fu, Q., Anderson, E. T., Zhang, S., Abbasov, M. E.*
J. Am. Chem. Soc. 2024 DOI: 10.1021/jacs.3c10741


2021

A proteome-wide atlas of lysine-reactive chemistry


Abbasov, M. E., Kavanagh, M., Ichu, T.-A., Lazear, M. R., Tao, Y., Crowley, V. M., am Ende, C. W., Hacker, S. M., Ho, J., Dix, M. M., Suciu, R., Hayward, M. M., Kiessling, L. L., Cravatt, B. F.
Nat. Chem. 2021, 13, 1081–1092.


2020

ENANTIOSELECTIVE, ORGANOCATALYTIC STRATEGY FOR THE OXAZOLOMYCIN CORE: FORMAL SYNTHESIS OF (+)- NEOOXAZOLOMYCIN


Chaheine, C. M., Gladen, P. T., Abbasov, M. E., Romo, D.
Org. Lett. 2020, 22, 9282–9286.

2019

Simplified immunosuppressive and neuroprotective agents based on gracilin A


Abbasov, M. E., Alvariño, R.; Chaheine, C. M.; Alonso, E.; Sánchez, J. A.; Conner, M. L.; Alfonso, A.; Jaspars, M.; Botana, L. M.; Romo, D.
Nat. Chem. 2019, 11, 342–350.



Gracilin A derivatives target early events in Alzheimer’s disease: effects on neuroinflammation and oxidative stress


Alvariño, R., Alonso, E., Abbasov, M. E., Chaheine, C. M., Conner, M. L., Romo, D., Alfonso, A., Botana, L. M.
ACS Chem. Neurosci. 2019, 10, 4102–4111.

2017

Enantioselective Diels-Alder-lactamization organocascades employing a furan-based diene


Abbasov, M. E., Hudson, B. M., Tantillo, D. J., Romo, D.
Org. Biomol. Chem. 2017, 15, 3179–3183.



Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application


Abbasov, M. E., Hudson, B. M., Tantillo, D. J., Romo, D.
Chem. Sci. 2017, 8, 1511–1524.

2014

Acylammonium salts as dienophiles in Diels-Alder/lactonization organocascades


Abbasov, M. E., Hudson, B. M., Tantillo, D. J., Romo, D.
J. Am. Chem. Soc. 2014, 136, 4492–4495.

2012

Effects of carbon nanotubes on electro-optical properties of dye-doped nematic liquid crystal


Abbasov, M. E., Carlisle, G. O.
J. Mater. Sci.: Mater. Electron. 2012, 23, 712–717.

2010

Hybrid carbon nanotube and dye-doped liquid crystal material for holographic imaging


Abbasov, M. E., Ghosh, S., Quach, A., Carlisle, G. O.
J. Mater. Sci.: Mater. Electron. 2010, 21, 854–859.



Optical properties of permanent gratings in liquid crystal doped with dye and carbon nanotube


Suleiman, Y. S., Ghosh, S., Abbasov, M. E., Carlisle, G. O.
J. Mater. Sci.: Mater. Electron. 2008, 19, 662–668.


2023

Phloroglucinol meroterpenoids and derivatives as lysine-targeting agents and uses thereof


Bracken, A. K., Gekko, C. E., Abbasov, M. E.
Provisional patent application filed on September 27, 2023.


2018

Gracilin A and congeners as immunosuppressive and neuroprotective agents


Abbasov, M. E., Alvariño, R., Alonso, E., Sánchez, J. A., Alfonso, A., Botana, L. M., Romo, D.
U.S. Application No. 62/638,856 (WO/2019/173382). March 5, 2018.